data_FAM_000108 # _pdbx_reference_molecule_family.family_prd_id FAM_000108 _pdbx_reference_molecule_family.name "Ac-LAAQcmph inhibitor" _pdbx_reference_molecule_family.release_status REL _pdbx_reference_molecule_family.replaces ? _pdbx_reference_molecule_family.replaced_by ? # loop_ _pdbx_reference_molecule_list.family_prd_id _pdbx_reference_molecule_list.prd_id FAM_000108 PRD_000235 # loop_ _pdbx_reference_molecule_synonyms.family_prd_id _pdbx_reference_molecule_synonyms.prd_id _pdbx_reference_molecule_synonyms.ordinal _pdbx_reference_molecule_synonyms.source _pdbx_reference_molecule_synonyms.name FAM_000108 PRD_000235 1 PMID:17599357 acetyl-leucyl-alanyl-alanyl-ketomethyl(cycloglutamine)-phthalhydrazide FAM_000108 PRD_000235 2 PMID:17599357 Ac-LAAQcmph # loop_ _pdbx_reference_molecule_annotation.family_prd_id _pdbx_reference_molecule_annotation.prd_id _pdbx_reference_molecule_annotation.ordinal _pdbx_reference_molecule_annotation.source _pdbx_reference_molecule_annotation.type _pdbx_reference_molecule_annotation.text FAM_000108 PRD_000235 1 PMID:17599357 function "inhibitor of Replicase polyprotein 1ab (pp1ab), EC: 3.4.22.-," FAM_000108 PRD_000235 2 PMID:17599357 "Mechanism of action" "form an unusual thiiranium ring with the nucleophilic sulfur atom of Cys145, trapping the enzyme's catalytic residues in configurations similar to the intermediate states" # loop_ _pdbx_reference_molecule_features.family_prd_id _pdbx_reference_molecule_features.prd_id _pdbx_reference_molecule_features.ordinal _pdbx_reference_molecule_features.source_ordinal _pdbx_reference_molecule_features.source _pdbx_reference_molecule_features.type _pdbx_reference_molecule_features.value FAM_000108 PRD_000235 1 1 PubChem External_Reference_ID 70698670 # loop_ _pdbx_family_prd_audit.family_prd_id _pdbx_family_prd_audit.date _pdbx_family_prd_audit.processing_site _pdbx_family_prd_audit.action_type FAM_000108 2012-02-08 RCSB "Create family" FAM_000108 2013-10-16 RCSB "Initial release" #